The United States uses biological fluorescent proteins to observe the movement of proteins in neurons. According to the physicist organization network on August 22, a research team at the University of Southern California recently used the biological fluorescent protein isolated from the jellyfish to illuminate the interior of the neuron. And a video was shot, revealing the scene of the protein moving indoors in the nerve cell area, you can "see" the protein through the neurons and the process of brain reconstruction. Related papers were recently published in the journal "Cell? Report". There are two types of neuronal compartments: axon and dendrite. Axons are areas responsible for transmitting electrical signals to other neurons, while dendrites are areas that receive signals from other neurons. The lead author of the thesis, Ph.D. student of the University of Southern California, Samander? Albasam said: "People know that proteins have a special orientation, and can only enter one of the compartments. How did it happen until we witnessed how they moved to one of the compartments. "In the mid-1990s, scientists isolated green fluorescent protein (GFP) from jellyfish. When GFP is exposed to blue light, it emits bright green fluorescence. Labeling with GFP allows people to see proteins inside cells and neurons. But because there are many different and overlapping paths in neurons, it has not been possible to see the flow of proteins inside neurons. Albasam and colleagues have developed a new technology that allows people to further see how proteins are directed into one of the two compartments. By blocking a single path, they accumulate GFP-filled transport bubbles. A transport bubble is a small bubble that carries membrane proteins and can move up and down in nerve cells. Then use a small molecule drug to make these accumulated luminous transport bubbles suddenly released under a strong light pulse. Corresponding author of the paper, Dorn Arnold, Associate Professor of Molecular and Computational Biology at the University of Southern California ’s Don Saif College of Liberal Arts and Sciences, explained: "The results are very surprising. We found that the transport bubbles carrying membrane proteins should enter the dendrites. At the beginning, the dendritic compartment was targeted, but both compartments entered. But those who entered the axon compartment stopped quickly and were prevented from further penetration. "Proteins are the basic building materials that make up the brain. "The human brain is constantly breaking down and rebuilding every day. After a week from today, the proteins that make up the brain will be completely different from today." Arnold said, "This video shows the process of brain reconstruction. Previously we just knew This process now really sees this scene. "
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